We identify a family of hemoglobin-derived peptides that are elevated in CQR parasites and show that peptide accumulation, drug resistance, and reduced parasite fitness are all linked in vitro to CQR alleles of the P
In the past, chloroquine was used widely as a prophylactic agent to prevent Plasmodium infection
Methemoglobinemia (MetHb) is a blood disorder in which an abnormal amount of methemoglobin is produced
, 1989, increased masking of the lipid that
Studies have indicated chloroquine is effective against the trophozoites of Entamoeba histolytica (E
DV is a lysosomal isolated acidic Quinoline-containing antimalarial drugs, such as chloroquine, quinine and mefloquine, are mainstays of chemotherapy against malaria
In this study, most of the observed
It is sold under the brand name Aralen, and it is also sold as a generic medicine
FP is an oxidized form of heme which is toxic for biological membranes
Methemoglobin
malariae, P Chloroquine is an antimalarial drug also used for the treatment of severe rheumatoid arthritis, systemic lupus erythematosus, and other dermatological diseases
Chauhan VS